Research Summary
Magnetic resonance imaging, gene expression, neuroanatomy
Profile
Biology of Neurodegenerative Disorders
We are investigating the biology of neurodegenerative disorders in normal elderly and people with Alzheimer's disease and other forms of dementia in collaboration with Professors Barbara Wold and Long Cai and their laboratories untilizing RNA-Seq, Seq-FISH and immunocytochemistry. Our data reveal reduction in the capacity to maintain healthy axons and in the regulation of blood flow in the early stages of dementia that could be part of the pathogenesis of this disorder.
Publications
Books
- The Human Illnesses by Peter C. Williamson and John Allman, Oxford University Press, New York, 2011.
- Evolving Brains by John Allman, Scientific American Library - W. H. Freeman, New York, 2000. Download