Non-coding RNAs: Study of natural functions of non-coding RNAs in the cell and programming of RNA pathways for new functions in vivo. Non-coding RNAs as determinants of epigenetic states. The link between RNA- and chromatin-based epigenetic mechanisms.
Assistant Professor of Biology and Biological Engineering
We are interested in biophysical principles and molecular mechanisms relevant to cilia biology and diseases. We also have other exciting projects on leveraging cellular cryo-electron tomography (cryoET) and AlphaFold2-assisted modeling to address various biology questions. Our guiding principle is: if you do not know what that protein is or how it functions inside the cell, just look at the thing at high resolutions.
Centennial Professor of Aeronautics and Mechanical Engineering
John Dabiri’s research focuses on unsteady fluid mechanics and flow physics, with particular emphasis on topics relevant to biology, energy, and the environment. Current interests include biological fluid dynamics in the ocean, next-generation wind energy, and development of new experimental methods.
Charles and Mary Ferkel Professor of Chemistry, Materials Science, and Applied Physics
Quantum chemistry, molecular dynamics, statistical physics: simulation and design of biological, polymer, ceramic, and metal systems; Reaction mechanisms in homogeneous and heterogeneous catalysis; Prediction of Protein Structure and Function; Nanotechnology, bionanotechnology
Ethel Wilson Bowles and Robert Bowles Professor of Chemistry and Chemical Engineering; Merkin Institute Professor; Director of the Jacobs Institute for Molecular Engineering for Medicine
Global health; Microbial communities and biophysics of the gut microbiome; Diagnostics and Antimicrobial Susceptibility Testing (AST); Microfluidics and single-molecule and single-cell analyses; Complex networks of reactions, cells and organisms.
Bren Professor of Biology and Chemistry; Merkin Institute Professor
Mayo's focus has been the coupling of theoretical, computational, and experimental approaches for the study of structural biology. In particular, he has placed a major emphasis on developing quantitative methods for protein design with the goal of developing a fully systematic design strategy.
James Irvine Professor of Environmental Science and Geobiology; Allen V. C. Davis and Lenabelle Davis Leadership Chair, Center for Environmental Microbial Interactions; Director, Center for Environmental Microbial Interactions
Designing and constructing artificial molecular systems that exhibit programmable behaviors such as recognizing molecular events from their environment, processing information, making decisions, taking actions, learning, and evolving
The ubiquitin-proteasome system; N-degron pathways of protein degradation (previously called “N-end rule pathways”); selective targeting of cancer cells through cancer-specific DNA deletions or insertions; molecular cause(s) of sleep; new biochemical and genetic methods.